Canasta by MeggieSoft Games - Play online or against your computer.
MeggieSoft Games Canasta is a comprehensive two-player implementation supporting both the Classic and Modern American rules. Play against an online opponent or against your computer. Canasta has a rich user interface with many customizable visual, audio, and game options
Canasta is a game of taking and melding cards with the object of scoring more points than your opponent. The first player to 5000 points wins the game.